Immunity

1. Cells that produce antibodies are:
a. APC
b. Plasma cells
c. Helper T cells
d. Cytotoxic T cells
e. Natural killer cells

2. Cells that kill virus-infected cells without antibodies are:
a. APC
b. Plasma cells
c. Helper T cells
d. Cytotoxic T cells
e. Natural killer cells

3. Cells that phagocytize antigens are:
a. APC
b. Plasma cells
c. Helper T cells
d. Cytotoxic T cells
e. Natural killer cells

4. Cells that bind to antigen-MHC II complex are:
a. APC
b. Plasma cells
c. Helper T cells
d. Cytotoxic T cells
e. Natural killer cells

5. How many different types of IgG molecules can be made from a gene with 5 Vs, 6Ds, 4Js, and 5Cs?
a. 0
b. 20
c. 120
d. 600
e. Too many to count

6. Interleukins cause proliferation of all of the following except:
a. Helper T cells
b. Pre-killer cells
c. B cells
d. Antigen-presenting cells
e. None of the above

7. Activation of B cells requires all of the following. Which is the third step?
a. A bound antigen is taken in by the B cell
b. A helper T cell binds an antigen-MHC II complex
c. An antigen is digested
d. IL-2, IL-4, IL-5, and IL-6 are released
e. A B cell divides

8. The secondary immune response is due to:
a. Memory B cells
b. Memory T cells
c. Antigen-presenting cells
d. Vaccination
e. a and b

9. If you examined the blood of a patient with AIDS, which one of the following would you find?
a. Antibodies
b. No antibodies
c. Too many regulatory T cells
d. No cytotoxic T cells
e. None of the above

10. Patients with an inherited type of colon cancer called familial adenomatous polyposis have a mutation in the gene that codes for:
a. Apoptosis
b. IgE antibodies
c. Helper T cells
d. ADCC
e. Phagocytosis

11. Which statement is incorrect?
a. The variable region of a heavy chain binds with antigen
b. The variable region of a light chain binds with antigen
c. The Fc region attaches to a host cell
d. The constant region of a heavy chain is the same for all antibodies
e. None of the above

12. Immune deficiencies are caused by all of the following. Which one does not cause an acquired immune deficiency?
a. Chromosomal-linked B-cell deficiency
b. Cyclosporin to inhibit IL-2 secretion
c. HIV infection
d. Rapamycin to inhibition IL-2 action
e. None of the above

13. Antibodies for serological testing can be obtained from all of the following except:
a. Vaccinated humans
b. Vaccination animals
c. Monoclonal cultures
d. Viral cultures
e. None of the above

14. If a patient shows the presence of antibodies against Herpes simplex, this indicates all of the following except:
a. The patient may have the disease
b. The patient may have had the disease and has recovered
c. the patient may have been vaccinated
d. A recent transfusion may have passively introduced the antibodies
e. The patient was near someone who had the disease

15. Which of the following is not a characteristic of B cells?
a. They originate in bone marrow
b. They have antigen receptors on their surfaces
c. They are responsible for the anamnestic response
d. they are responsible for antibody formation
e. None of the above