15L-bioreactor University of British Colombia		Christine L. Case Biology Skyline College Industrial Microbiology    This course integrates applications and products to illustrate the processes and techniques of industrial fermentation. The importance of GLPs and quality control are included in discussions of getting a product to market.
Anatomy of a benchtop fermenter		Things to do to prepare for class

History and fermentation   Fermentation & Human History Beer Chocolate		Definitions of industrial microbiology, fermentation, and biotechnology From pre-Colombian Americas to Pasteur, Takamine, and Weizmann Bread, beer, Asian foods Butyl alcohol-acetone fermentation Natural processes and mixed culture fermentations Chocolate Malo-lactic fermentation in wine Pure cultures Microbial metabolism Primary and secondary metabolites Penicillin Ethyl alcohol Bacteriocins & dairy fermentations
Technology and microbial growth   Discover a new antibiotic Industrial ferm. lab exp.		Media CHONPS, growth factors, & trace elements Superoxide dismutase Taxol Liquid v. solid-substrate fermentations Koji process Citric acid production Cell cultures (bacteria, fungi) Bacillus thuringiensis Pseudomonas syringae Growth and synchronous culture Spectrophotometry Plate counts Bioreactors, fermenters, and chemostats Batch-fed, continuous, perfusion Contamination and its control Foam out Scale-up Immobilized enzymes Aspartic acid and aspartame
Designing products and microbial genetics		Selection MSG Cellulase Detergent enzymes & Other industrial enzymes Screening for natural products Antibiotics Antimicrobial peptides Making mutants: additions, deletions, site-directed mutagenesis Subtilisins Evolution Selection Xanthan Directed evolution Site-directed mutagenesis PCR Peroxidase Genetic engineering Vectors and recombinant DNA Induction Secretion Gene and product stability Hepatitis B vaccine Renninase Agrobacterium & the Ti plasmid Antisense DNA Endless Summer Post-harvest modification Penicillin
Products		Pharmaceutical Agricultural Food Recreational Designer jeans
Environmental applications		Bioremediation & Wastewater treatment Vacuum heap BXT Bioconversion Gasahol, methane Global warming Methanogens and methanotrophs Conversions to useful products Anaerobic reactors Paper, whey Biosensors Mercury, penicillin
Extremophiles		New enzymes for manufacturing processes Protein computer chips